【 Intestinal health 】 Study on moistening and laxative effect of fructooligosaccharide

2024-01-25
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Intestinal flora plays an important role in the occurrence and development of constipation, and constipation is often accompanied by disorders of intestinal flora. Oligofructose is a high-quality prebiotic and dietary fiber, which is stable in nature and not digested by gastrointestinal endogenous enzymes, and can improve the balance of intestinal flora to prevent and control constipation.

1. Fructooligosaccharides and probiotics

Oligofructose (FOS), widely found in nature, such as pears, honey, beer, bacteria, yeast, onions, parsnips, burdock, bananas, wheat, rye, oats, snowdrops, etc. contain FOS, snowdrops in the root of the oligofructose content of the highest content of all plants, 45% to 65% of the content of the dry matter of the oligofructose, so the snowdrops have the "King of oligofructose". Oligofructose is an excellent water-soluble dietary fiber, the human gastrointestinal tract does not hydrolyze this oligosaccharide enzyme system, so it is not easy to be digested and absorbed by the gastrointestinal and directly into the large intestine priority for the bifidobacteria use, is conducive to bifidobacteria proliferation, is currently recognized as a prebiotic. It is now widely accepted that a person consuming prebiotics 10-15g/d can obtain intestinal health, and intake of less than l5g/d is safe for human beings. The 100 subjects were randomly divided into a test group and a blank control group, the test group took 10-20 ml of oligofructose per day, and the number of bifidobacteria and lactobacilli in the intestinal tract of the test group increased significantly after the test group was tested for 14 consecutive days, and the differences were statistically significant (P<0.01), which indicated that oligofructose has the function of regulating human intestinal flora and proliferating bifidobacteria and lactobacilli. The role of oligofructose. Several studies have shown that oligofructose can promote the growth of Bifidobacterium and Lactobacillus in rat intestinal tract.

 2. The role of oligofructose in the prevention and treatment of constipation

As a water-soluble dietary fiber, oligofructose is in solution in the intestinal tract and has good water holding capacity, and it is easy to be fermented by intestinal bacteria to produce acetic acid, propionic acid, butyric acid and other short-chain organic acids, which can reduce intestinal pH, stimulate the intestinal mucosa and promote intestinal peristalsis to laxative and laxative, improve fecal character, prevent and alleviate the effects of constipation; it also promotes the proliferation of the probiotic bacteria Bifidobacterium bifidum and Lactobacillus lactis and inhibits the growth of harmful bacteria and pathogenic bacteria such as Salmonella and spoilage bacteria in the intestine, thereby improving the balance of intestinal flora and preventing constipation. It promotes the proliferation of probiotic bifidobacteria and lactobacilli in the intestinal tract, inhibits the growth of harmful bacteria and pathogenic bacteria such as salmonella and spoilage bacteria in the intestinal tract, thus improving the balance of intestinal flora and preventing constipation. Bifidobacterium oligofructose synbiotic preparation was administered to 49 patients with constipation, of which 38 cases (77 5.%) had their symptoms disappeared, 5 cases (10 2.%) had their symptoms significantly improved, and 6 cases (12 3.%) had no effect. The results of the study showed that when 1.0g/(kg-d) oligofructose was fed to rats, it showed laxative effect, and had better effect on maintaining the balance of intestinal flora and inhibiting the growth of enterococci and enterobacteria. The sweetness of oligofructose is only 1/3 of sucrose, it is not decomposed by a amylase, sucrose converting enzyme and maltase in human body, it can't be utilized by human body as an energy source, and it won't increase blood sugar, each gram of oligofructose contains only 6.3kJ of calories, so it is very suitable for diabetic patients and obese people, daily intake of 3 3g oligofructose has the effect of regulating human intestinal flora, activating probiotic bacteria and inhibiting the growth of harmful bacteria. The role of harmful bacteria. Generally speaking, the consumption of oligofructose pure products in 30g/d or less will not produce any adverse effects, and through animal experiments found that long-term intake of oligofructose will also produce side effects.

3.epilogue
Oligofructose is a natural active substance,an excellent dietary fiber,with the progress of society,people pay more attention to health care and food safety,the use of dietary fiber to improve constipation has become a hot spot in people's research,the use of oligofructose in the natural composition of the food to promote the growth of intestinal probiotic bacteria,increase the water content in the intestinal tract,improve constipation,for the study of constipation to improve the method to provide some new ideas.