Latanoprost Tris(triethylsilyl) Ether
CAS No. 477884-78-9
MF: C44H82O5Si3
Molecular weight 775.38
MF: C44H82O5Si3
Molecular weight 775.38
API404
Quantity
Latanoprost Tris-triethylsilyl-Ether is a chemically modified derivative of latanoprost,
a widely used prostaglandin analog for treating glaucoma and ocular hypertension.
this compound serves as a reference standard or analytical impurity in pharmaceutical research and quality control processes.
Latanoprost Tris-triethylsilyl-Ether is primarily utilized to ensure the purity, stability, and consistency of latanoprost-based formulations during manufacturing and regulatory evaluations.
Pharmaceutical Quality Control
As a high-purity reference material, Latanoprost Tris-triethylsilyl-Ether enables precise identification and quantification of impurities in latanoprost drug products. It is critical for compliance with ICH guidelines (e.g., Q3A/B) on impurity profiling and batch-to-batch consistency.
As a high-purity reference material, Latanoprost Tris-triethylsilyl-Ether enables precise identification and quantification of impurities in latanoprost drug products. It is critical for compliance with ICH guidelines (e.g., Q3A/B) on impurity profiling and batch-to-batch consistency.
Analytical Method Development
This compound is used to validate chromatographic methods (e.g., HPLC, LC-MS) for detecting trace impurities in ophthalmic formulations. Its unique silyl ether modification enhances stability during analysis, ensuring reliable results in method qualification studies.
This compound is used to validate chromatographic methods (e.g., HPLC, LC-MS) for detecting trace impurities in ophthalmic formulations. Its unique silyl ether modification enhances stability during analysis, ensuring reliable results in method qualification studies.
Latanoprost Tris-triethylsilyl-Ether Stability Testing
Latanoprost Tris-triethylsilyl-Ether aids in assessing degradation pathways of latanoprost under varying storage conditions (e.g., temperature, humidity). This data supports shelf-life determination and packaging optimization for commercial products.
Latanoprost Tris-triethylsilyl-Ether aids in assessing degradation pathways of latanoprost under varying storage conditions (e.g., temperature, humidity). This data supports shelf-life determination and packaging optimization for commercial products.
Latanoprost Tris-triethylsilyl-Ether Regulatory Submissions
Pharmaceutical companies include this compound in regulatory filings (e.g., ANDA, NDA) to demonstrate comprehensive impurity control strategies, meeting requirements from agencies like the FDA and EMA
Pharmaceutical companies include this compound in regulatory filings (e.g., ANDA, NDA) to demonstrate comprehensive impurity control strategies, meeting requirements from agencies like the FDA and EMA
