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Sotorasib

Sotorasib

CAS NO.: 2296729-00-3
MF: C30H30F2N6O3
API234
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Product Name
Sotorasib
Appearance
White powder
Specification
 99%
Test Method
HPLC
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Shelf Time
24 months
  Solubility  DMSO : 100 mg/mL (178.38 mM; Need ultrasonic)

Sotorasib (AMG510) is a chiral compound and a potent KRAS G12C covalent inhibitor with potential antitumor activity.

Sotorasib is an experimental KRAS inhibitor being investigated for the treatment of
KRAS G12C mutant non small cell lung cancer, colorectal cancer, and appendix cancer.
 
Sotorasib is indicated in the treatment of KRAS G12C-mutated locally advanced
or metastatic non-small cell lung cancer (NSCLC) in adults who have received at least one prior systemic therapy.