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Pemetrexed Disodium

Pemetrexed Disodium

CAS NO.:150399-23-8
MF:C20H22N5NaO6
EINECS NO.:604-733-2
API162
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Product Name
Pemetrexed Disodium
Appearance
White powder
Specification
 99%
Test Method
HPLC
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Shelf Time
24 months

Pemetrexed is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively

Pemetrexed disodium (marketed as ALIMTA®, “pemetrexed”) is a novel, multi-targeted antifolate.
It suppresses tumor growth by impeding both DNA synthesis and folate metabolism.
Pemetrexed disodium has demonstrated promising clinical activity in a wide variety of solid tumors, including non-small cell lung,
breast, mesothelioma, colorectal, pancreatic, gastric, bladder, cervix, and head and neck.