Oxytetracycline hydrochloride
CAS: 2058-46-0
MF: C22H25ClN2O9
EINECS No. : 218-161-2
MF: C22H25ClN2O9
EINECS No. : 218-161-2
API367
Quantity
Oxytetracycline hydrochloride is a salt prepared from oxytetracycline taking advantage of the b
asic dimethylamino group which protonates readily to form the salt in hydrochloric acid solutions.
The hydrochloride is the preferred formulation for pharmaceutical applications.
Like all tetracyclines, oxytetracycline shows broad spectrum antibacterial and antiprotozoan activity
and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.
Oxytetracycline hydrochloride is an antibiotic indicated for treatment of infections caused by
Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae,
Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae.
It is used in studies on the oxytetracycline-resistance gene (otrA).
