Hit Enter to search or Esc to close
0
Mexiletine hydrochloride

Mexiletine hydrochloride

CAS NO.: 5370-01-4
MF: C11H18ClNO
EINECS NO.:226-362-1
API142
Quantity
Send Inquiry
add to cart

Product Name
Mexiletine hydrochloride
Appearance
White or white crystalline powder
Specification
 99%
Test Method
HPLC
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Shelf Time
24 months
  Solubility  Ethanol: 50 mg/mL
 Acidity coefficient (pKa)  9.0(at 25℃)

Mexiletine hydrochloride is a class 1B antiarrhythmic agent used in the treatment of documented ventricular arrhythmias that warrant treatment.

Mexiletine hydrochloride, like class I antiarrhythmicagents, blocks the fast Na channel in cardiac cells.

It isespecially effective on the Purkinje fibers in the heart.

Thedrug increases the threshold of excitability of myocardialcells by reducing the rate of rise and amplitude of the actionpotential and decreases automaticity.

Mexiletine hydrochloride is used for long-term oral prophylaxisof ventricular tachycardia.

Mexiletine hydrochloride is used for the treatment of ventricular tachycardia and symptomatic premature ventricular beats, and prevention of ventricular fibrillation.