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Efinaconazole

Efinaconazole

CAS NO.: 164650-44-6
MF:C18H22F2N4O
EINECS NO.:813-597-5
API328
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Product Name
Efinaconazole
Appearance
White to beige powder
Specification
 99%
Test Method
HPLC
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Shelf Time
24 months
  Solubility   Chloroform (Slightly), Methanol (Slightly)
  pKa  12.11±0.29(Predicted)

Efinaconazole is a broad-spectrum triazole antifungal agent with activity against Acremonium,

Aspergillus, Candida, Cryptococcus, Epidermophyton, Fusarium, Microsporum, Paecilomyces,

Pseudallescheria, Scopulariopsis, Trichophyton, and Trichosporon.

Efinaconazole has been used as:
a topical anti-onychomycosis drug to determine its effects on Trichophyton rubrum and Trichophyton interdigitale
as an anti-fungal agent to study its permeability into the nail lysates
as an anti-fungal agent to study its effects on Candida africana and Candida dubliniensis