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Acalabrutinib

Acalabrutinib

CAS NO.: 1420477-60-6
MF: C26H23N7O2
EINECS NO.: 814-272-0
A229
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Product Name
Acalabrutinib
Appearance
Yellow powder
Specification
 99%
Test Method
HPLC
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Shelf Time
24 months
  Solubility  Dissolved in DMSO (at least 25 mg/ml)
  Acidity coefficient (pKa)
 		  11.47±0.70(Predicted)

Acalabrutinib is a Bruton Tyrosine Kinase inhibitor that prevents the proliferation, trafficking, chemotaxis,

and adhesion of B cells.6 It is taken every 12 hours and can cause other effects such as atrial fibrillation,

other malignancies, cytopenia, hemorrhage, and infection

Acalabrutinib is a Bruton tyrosine kinase inhibitor used to treat mantle cell lymphoma,
chronic lymphocytic leukemia, and small lymphocytic lymphoma.