Cloprostenol Isopropyl Ester: Properties, Applications and Safety Guide

2025-03-26
1. Basic chemical properties
Chemical formula: C25H35ClO6
Molecular weight: 466.99 g/mol
CAS number: 157283-66-4
Physical form: Colorless to pale yellow oily liquid, must be stored at -20℃ away from light (in an inert gas environment), slightly soluble in chloroform, DMSO and methanol.
COA of cloprostenol isopropyl ester
2. Action and Use
Main Application:
Veterinary field: used to regulate the reproductive cycle of animals (such as inducing estrus, synchronous ovulation) or treat postpartum uterine diseases.
Biochemical research: as an experimental reagent, to study the mechanism of action and signaling pathway of prostaglandin receptors.
Mechanism of action: by binding to prostaglandin receptors, triggering uterine smooth muscle contraction and corpus luteum dissolution, thereby regulating reproductive function.
Structural advantages: the isopropyl ester group may enhance its lipid solubility, prolong the drug action time or improve stability.
 cloprostenol isopropyl ester
3. Pharmacological action and effect
Mechanism of action: as a synthetic analogue of PGF2α, Cloprostenol Isopropyl Ester regulates reproductive function by binding to prostaglandin receptors, promoting uterine smooth muscle contraction and corpus luteum dissolution.
Clinical effect: in animal models, similar drugs are often used to shorten delivery time or treat postpartum uterine infection. Its isopropyl esterification may increase lipid solubility and enhance tissue permeability.
4. Potential side effects and risks
Although specific side effect data are limited, based on the commonality and safety information of prostaglandins, the following risks should be noted:
Effects on the reproductive system: May cause excessive uterine contractions, leading to abdominal pain or risk of miscarriage (especially in pregnant animals).
Toxic reactions: According to the GHS classification, this compound is harmful if swallowed (H302), and direct contact or ingestion should be avoided.
Operational protection: It is recommended to wear gloves and goggles, ensure good ventilation, and prevent inhalation or skin contact.
5. Safe operation and transportation recommendations
Storage conditions: Strictly store at -20℃ away from light, avoid repeated freezing and thawing to maintain stability 310.
Transportation requirements: Low temperature cold chain transportation is required, leak-proof containers and inert gas protection are used, and compliance with hazardous chemical transportation regulations is required.
Regulatory compliance: Before export, it is necessary to confirm the chemical import regulations of the target country, provide MSDS (Material Safety Data Sheet) and purity certificate (≥98%).

Xi'an Rui Zelin Bio Tech Inc. Was Established In 2004 And Has More Than 17 Years Of Experience In Import And Export  Of Foreign Trade. It Is a Large-Scale Gold Supplier Integrating Production And Sales. We Also Provide  Api,Vitamins,Cosmetic Ingredients Manufacturing Service.
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All products are in accordance with international standards,  with more than five years of experience in technical inspection personnel, with advanced testing equipment,  with their own independent, fully equipped testing laboratory,  and strive to provide customers with high quality products and services.
At present, the hot product cloprostenol isopropyl ester widely used in medicine and other aspects.
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Conclusion:
As a natural active ingredient of citrus plants, nobiletin has shown broad application prospects in the health industry. Its multiple functions and safety make it an ideal raw material for the development of functional foods, medicines and cosmetics.