Amoxicillin
CAS No. 26787-78-0
Molecular Formula C16H19N3O5S
EINECS No. 248-003-8
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Amoxicillin, a semi-synthetic broad-spectrum antibiotic, belongs to the penicillin class and is a derivative of Penicillin G.
As a beta-lactam antibiotic, Amoxicillin is renowned for its efficacy against a wide range of Gram-positive and Gram-negative bacteria.
Its enhanced oral bioavailability and acid stability make it a first-line treatment for numerous infections.
Amoxicillin is often combined with clavulanic acid (as Amoxicillin-Clavulanate) to overcome beta-lactamase-mediated resistance, further expanding its therapeutic utility.
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Bacterial Cell Wall Disruption: Amoxicillin inhibits peptidoglycan synthesis, weakening bacterial cell walls and causing cell lysis.
Broad-Spectrum Activity: Effective against Streptococcus, Staphylococcus (non-penicillinase-producing strains), Haemophilus influenzae, E. coli, and Helicobacter pylori.
High Oral Bioavailability: Unlike many penicillins, Amoxicillin is stable in stomach acid, achieving rapid absorption and high serum concentrations.



